What are DNA Sequence Motifs Why are They Important Essay

What are DNA sequence motifs? Why are they important? DNA sequence motifs are used to profile a genomic region in DNA. They are characterized as short nucleotide patterns and are conserved at biologically related genomes. The complexity of these patterns ranges from a simple and short subsequence (5-20 bp long) to palindromic and space dyed subsequences. In essence, motifs are considered as a means of enciphering DNA and are key element for defining regulatory networks and further understand the interactions between transcription factors and DNA []. How are motifs formulated? There are several models that could be used to represent a sequence motif, including but not limited to consensus sequences and position weight matrices (PWMs).†¦show more content†¦This is typically addressed by experimentation .e.g. observing protein interaction with DNA at small-scale genomic regions. It is shown that such experiments are efficient and yield reliable results, especially when applied on simple genomic sequences. But, their performance degrades as the genomic complexity of the cell increases. To overcome this issue, phylogenetic footprinting (cross-species genomic analysis) is used []. II.Motif Detection Having obtained the set of putative genomes (from I), we would like to extract the signals that occur at all sequences (the motifs). This is a challenging task, because it depends on various factors, such as the quality of the sequences, and it has some unknown parameters, like the size and orientation of the motifs. There are two main methods used to address this problem[]:- Word-based analysis Algorithms that fall in this category exhaustively search for overrepresented patterns by inspecting all possible subsequences. These algorithms are likely to obtain a globally optimal motifs. 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Glamourous Free Essays

Dylon de Leon ENGL 100-08 QFRA 6-11 (pg. 186) Feb. 22, 2013 GLAMOUROUS What is glamour? How does it differ from looks, fame and fortune? In paragraph 12 of the article, the first few sentences are very effective. We will write a custom essay sample on Glamourous or any similar topic only for you Order Now They use 3 people that a lot of people know today and go straight to the point about who they are in the political world. This is an example of Givhan’s strategy that was shown to be effective. Givhan uses a few strategies throughout his article. One of the specific strategies was using famous and glamourous people that we see today as rich and famous and see as having fame and fortune. Another good strategy that he uses is pointing out the face between actors that they are not all what they seem and that who they really are isn’t who we see in public, and that what we are really seeing and who we really think they are is just an act. He points out that really glamour makes people forget about who they are and make everything seem so beautiful in the world. Givhan’s claim is simply that the people who we see living their lives full of fortune and happiness is simply not correct. He claims that glamour is just simply not all that great. Givhan states that glamour is situated in the now while cool is a step ahead. This claim makes perfect sense because glamour is just something that is seen in the moment and not in the future. Cool on the other hand is something that is seen outside of what is on the big screen, therefore is seen in more than just the present. It may just be the way that I look at it that makes sense. You can tell the difference between Glamour, Charisma, and cool, by what they show and what makes each characteristic what it is. Glamour is a sort of fairytale, Charisma is personal, and cool is just, well, cool. If someone was to want to be cool, I would suggest that they do something to inspire people as a famous person. Cool isn’t about having lots of stuff and looking good, there is a big difference. To be cool, you have to show the people that you are cool and show the people you are more than just good looks. How to cite Glamourous, Papers

Neighbors Are the People Who Live Near Us. in Your Opinion, What Are the Qualities of a Good Neighbor free essay sample

Neighbours are the people who live near us, and their behaviour influences our daily lives. Good neighbours can make us feel comfortable and help us, and everyone benefits from a good relationship with neighbours. In my point of view, there are three conspicuous aspects of the qualities of a good neighbour. One of the most important characteristics of good neighbours is that they have good living habits and are friendly to others. A person with bad habits will affect one’s daily life. For example, children are most likely to be influenced by bad neighbours and acquire bad habits. Also, they are hard to approach and difficult to get along with. Another important aspect of good neighbors is that they are likely to willing to help others. In our daily life, emergency situations may occur, and we may encounter difficulties which cannot be resolved by ourselves. At these times, the quickest help we can receive is probably from our neighbours. We will write a custom essay sample on Neighbors Are the People Who Live Near Us. in Your Opinion, What Are the Qualities of a Good Neighbor? or any similar topic specifically for you Do Not WasteYour Time HIRE WRITER Only 13.90 / page To some degree, neighbors are as important as relatives are to us, because they can provide immediate help. In the same way, a neighbor who is willing to help others will receive help in return. Helping each other can form friendly and harmonious relationships among neighbors. All in all, a good neighbors is someone who has a good living habit, is friendly and is willing to help others. Taking into account all of these factors, we may arrive at the conclusion that a good relationship among neighbors requires co-operation from both sides.

ASB †Antisocial Behaviour

ASB – Antisocial Behaviour Free Online Research Papers How effective are ASBO’s in preventing anti – social behaviour amongst the youth in today’s society? Introduction This project will focus upon the issues of anti-social behaviour looking at whether they have been successful, what effect Anti – Social Behaviour Orders have had on the community and examines if there is enough happening to deter the youth culture from anti – social and criminal behaviour towards society. ASBO’s were introduced under section one of the government’s Crime and Disorder Act 1998 and it came into force on April 1st 1999. However, since they were introduced there has been a lot of controversy in whether ASBO’s have actually been effective in deterring and punishing criminal behaviour. The project will go on to discuss the kind of problems anti-social behaviour causes on the streets today. It defines dispersal orders that only the police or the police community support officers can issue towards groups, what the consequences would be if they disobeyed the law before looking at a number of options that will be there to hand out depending on the circumstances and the crime. This could range from acceptable behaviour agreements (ABA) and acceptable behaviour contracts (ABC) to fixed penalty notices (FPN) and Penalty notice for disorder (PND) as ASBO’s are usually only handed out as a last resort. What agencies are now enforcing against ASB, what possession orders are? In addition, how the role of parents could make a difference if produced with parenting orders to underage minors. Aims The aim of this project is to investigate the background of ASBO’s and looking at whether they do actually work in stopping anti – social behaviour amongst the youth culture in today’s society. Hypothesis The hypothesis is that ASBO’s are not beneficial within society. Discussion of issues Whenever there are complaints or bad behaviour then theses are the first steps in trying to deter the youths from delinquency. Dispersal Orders Police and Police Community Support Officers (PCSO/s) can disperse people or groups from places where they appear to be behaving anti – socially, the removal period is for 24 hours but if they refuse to disperse then the officer can give them an order lasting for six months. If anyone is under the age of sixteen, the police or PCSO’s are legally obligated to take them to their place of residence (www.connexions-direct.com) however if there then becomes trouble the PCSO’s can subsequently hand out ABC/s or ABA/s. Acceptable Behaviour Contracts and Acceptable Behaviour Agreement An Anti – social behaviour contract (ABC) is a written voluntary agreement between the perpetrator and their local authority, ABC’s are intended to get the individual to acknowledge and accept their anti – social behaviour and the effect it has on society. The ABC contract outlines what the individual agrees not to do and what the penalty of their consequence will be if they do breach their contract. ABC’s and ABA’s can be used within the same age groups as ASBO’s, if they have to be used on children aged under ten then parent intervention may need to come into force like parenting orders and are useful in stopping low levels of ASB. They are informal as well as flexible therefore they are not legally binding and as a result, they can be issued for all types of ASB nevertheless, they would be used in court as evidence against an eviction or possession proceedings. (www.connexions-direct.com) Fixed Penalty Notices and Penalty Notice for Disorder Fixed penalty notices and penalty disorders are a one – off penalty issued to people who commit anti – social behaviour. FPN are generally dealt with environmental offences like noise, graffiti, dog fouling, and litter. FPN however comes with a standard fine, which can vary, towards  £40  £80 depending upon the offence, they can be issued by PCSO’s, and local council officers as well as certain other accredited people. They can be issued to any persons over ten years old. Penalty notices for disorder are issued for more serious crimes like misuse of fireworks or being drunk and disorderly PCSO’s and police can also issue these notices. However, Firth (2009) stated that this type of order would be given out to anybody who is sixteen or over and the fine depends on the severity of the crime. Having looked at the options that seriously considered before ASBO’s are issued, this project will now move on to discuss ASBO’s. Antisocial Behaviour Order The ASBO become about due to the growing behavioural problems in today’s youth culture, the official name is anti – social behaviour order. ASBO’s was initially designed to prevent these negative activities and stop specific anti – social behaviours. ASB covers a wide spectrum of problems and offences ranging from street drinking, drunken behaviour, dropping litter, loud music, verbal abuse even hanging around on street corners (Hale 2005). ASBO’s also covers the more serious matters such as hate crime that consists of racist or homophobic abuse, the key determinant in deciding whether particular behaviour is anti-social or not should be the impact of the behaviour towards others. (www.communities.gov.uk) ASBO’s are compared to the broken window theory outlined by Wilson and Kelling (1982) whereby they claim that if a broken window is left unrepaired then it leaves the building looking uncared for which then attracts the vandals. The theory suggests that in preventing crime it would be ideal to accomplish that with steps like keeping buildings in good repair, painting over graffiti and maintaining clean streets as well as responding effectively to petty street crime. (www.sociology.com) ASBO’s are a civil order that can only be issued through the courts, this order is strictly made against a person or person’s that have either participated or initiated in anti-social behaviour by causing or likely to cause harassment, intimidation, alarm, distress towards one or more people within the wider community, but not that of the same household (www.crimereduction.homeoffice.gov.org) The bar charts below show the number of ASBO’s in Cheshire, Merseyside, Greater Manchester and Greater London. (crimereduction.homeoffice.gov.uk) Number of anti – social behaviour orders issued to persons aged 10 – 17 year olds at court between April 99 to Dec 2007 The diagram below shows the percentage of children who actually obtain ASBO’s and the percentage that decide to go a different route. (crimereduction.homeoffice.gov.uk) Number of anti – social behaviour orders issued to persons aged 18+ at court between April 99 to Dec 2007 The charts are showing that, in the bigger cities of London and Manchester more ASBO’s where issued between 2003 – 2007 than in Cheshire and Merseyside. Anti – social behaviour is organised into three categories’ street scene, nuisance neighbours, and environmental crime. Street Scene The category of street scene ranges from Begging Anti social drinking Street prostitution Kerb crawling Marketing of drugs within the streets. (www.homeoffice.gov.uk) Nuisance Neighbour The category of nuisance neighbours Intimidation and harassment Noise Rowdy and nuisance behaviour Hoax calls Animal related problems Vehicle related nuisance (www.homeoffice.gov.uk) Over the years, there has been incredible support in helping to combat nuisance neighbours whereas a family would have a possession order issued upon them. They are orders issued by governed bodies that include local housing authorities, registered housing associations, housing co-operatives and Housing Action Trusts. Private landlords have a wide range of powers to help deal with anti-social behaviour that takes place in or is related to the homes they supply. The Anti-Social Behaviour Act 2003 enabled landlords to take immediate action in dealing with anti-social behaviour and protect the community by widening and strengthening housing injunctions. (www.communities.gov.uk) Environmental Crime The category of environmental crime Criminal damage / Vandalism Graffiti and fly posting Fly tipping Litter and waste Nuisance vehicles Drugs paraphernalia Firework misuse (www.homeoffice.gov.uk) This demonstrates that people can easily obtain an ASBO if they defy the law and become a nuisance against society. Advantages of ASBO’s In 2004 an unhinged youth was issued an ASBO that was due to run out in 2009, he was told that he could face up to five years in prison if he breached his restriction. However, it was reported that he was the very first person to ever have an ASBO revoked not only did he turn his life around, but the courts decided to lift the order and he got himself a job working as a mentor for other troubled teenagers. His ambition in life is to join the army or become a youth worker so it goes to prove that if you really want to turn your life around this demonstrates its possible, especially now with so much help available. (www.dailymail.co.uk) ASBO’s are meant to stop the perpetrator from going back to the places where they originally caused the trouble but it can sometimes be impossible if they work or go to school in that particular area. Therefore, there will be limits to what they can do at the times they will be there (www.responsiblecitizen.co.uk). Costs of ASBO’s In 2002 the reported cost of obtaining an ASBO averaged  £4,000 to  £5,000, whereas new studies has shown that the costs of ASBO’s have significantly reduced to costing  £2,500 including estimations of staff and legal expenses. Whenever an ASBO is breached or appealed the average cost then rises to a staggering  £5,350, but overall the police still think ASBO’s are cost effective compared to prison whereas not taking action against persistent anti – social behaviour has to have the highest cost of all. (www.asb.homeoffice.gov) Disadvantages of ASBO’s There has been a lot of criticism aimed towards ASBO’s and their effectiveness as many of those engrossed in the ASBO culture merely see it as a self fulfilling prophecy and consider ASBO’s as a badge of honour. This is however, a serious red flag area whereby some delinquents deliberately go out to accumulate ASBO’s in order to acquire street credibility, and by attainment it is purely seen as proof of standing within their peer groups (www.libdemvoice.org) The youth culture who see ASBO’s as a badge of honour may not however be too concerned by the stigma of gaining an ASBO and would therefore not care enough for the law in breaking their terms and conditions. However, if they do break their conditions they could be looking at up to two years in prison, everyone over the age of ten can and will be given an ASBO (www.responsiblecitizen.co.uk) Thugs who threaten violence and carry weapons are receiving ASBO’s and not handed harsher punishments like a prison sentence, carrying a knife or weapon constitutes at least five years in prison whereas giving them an ASBO is unacceptable. It is felt that ASBO’s are not reducing the levels of crime whereby stricter penalties and rehabilitation is what could be needed (www.thefreelibrary.com) Naming and shaming has been considered when handing out ASBO’s like they do with benefit fraud. However, naming the perpetrators presents the opportunities for their addresses to be exposed possibly leading to vigilante attacks, which would undoubtedly cause a lot more controversy throughout society and would only (www.caslon.com.au) After looking at the advantages and disadvantages of Asbo’s the project will now move on to looking at the agencies that are now tackling anti – social behaviour. Agencies tackling Anti – Social Behaviour There are lots of support from agencies that are working within partnership in trying to tackle and combat ASB effectively, they range from: Police and Community Support Officers Police Authority Probation Services Courts Crown Prosecution Services Fire and Rescue Services Health Services Street Wardens Youth Offending Teams Commercial Businesses Transport Providers These partnerships also include crime and disorder reduction partnerships, drug team actions and local strategic partnerships demonstrating that many authorities are determined to take a stand against ASB by doing whatever it takes to stop it from taking over the community in which they live and work in (www.asb.homeoffice.gov.uk). Apart from the above agencies, a parents’ role is to teach their children right from wrong and more importantly respect. However, this is evidently missing within dysfunctional families according to Squires and Stephen (2005). If the youth is under sixteen and breaks the law, then parenting orders could benefit the perpetrators’ from continuing to behave in an unacceptable manner. Parenting orders are imposed by the courts and they are given parenting contracts which enables interaction between themselves and certain support agencies that then sets out the standard of behaviour that is expected of the minor. The parents are required to attend courses, which may also include children attending school. They have to exercise control over their children’s offending behaviour by ensuring that they adhere to their curfew, however non-compliance of the above can lead to a  £1000 fine or any sentence that is available for a non – imprisonable offence. (www. direct.gov.uk) Conclusion In conclusion, the hypothesis was accepted. Findings show that not all ASBO’s that have been dispersed actually work in stopping a criminal act. Many of the youths act in an appalling manner just to obtain an ASBO for the reason that their friends have one, or they feel that their behaviour even if it is bad is the only thing that they have control over as they could be lacking something either from their home environment or within society itself. Anti–social behaviour can sometimes seem like a minor crime in the courtroom whereas graffiti, vandalism and harassment may seem trivial on a charge sheet, but behind those charges is a community living in fear besieged by reckless out of control minority of thugs. It is very intolerable that people are having to endure this type and level of ASB day in and day out feeling plagued in their own homes and not being able to go out and enjoy the public space within their community (Squires Stephen 2005). It costs around  £36,000 to lock somebody up for a year and prisons are already overcrowded (www.guardian.co.uk) so consequently if the government concentrated more on building and providing more centres were youths could entertain themselves within a controlled environment then many of the offenders would not go off the rails. Hale (2005) claimed that the majority of problems stemmed from boredom and if that could be combated then the chances are it could cause a decline towards Anti-social behaviour overall. Research Papers on ASB - Antisocial BehaviourCapital PunishmentThe Relationship Between Delinquency and Drug UseThree Concepts of PsychodynamicRelationship between Media Coverage and Social andBionic Assembly System: A New Concept of SelfUnreasonable Searches and SeizuresRiordan Manufacturing Production PlanQuebec and CanadaInfluences of Socio-Economic Status of Married MalesIncorporating Risk and Uncertainty Factor in Capital

10 of the biggest workplace time wasters

10 of the biggest workplace time wasters Office  distractions are endless at work. We spend a lot  of time surfing the web, checking in on social media, while still holding small talk at the water cooler. These â€Å"little† breaks throughout the day can add up in time you are supposed to be getting work done and it can waste productivity in the office. These workplace time wasters can affect your work ethic and quality of work you produce. It’s time to cut out these time wasters and focus on the task ahead. Here are 10 of the biggest workplace time wasters. How many of these are you guilty of doing throughout the day?Source [Yast]

The future of electric vehicles Research Paper Example | Topics and Well Written Essays - 2000 words

The future of electric vehicles - Research Paper Example Replacing such vehicles with the ones that use electric energy will bring positive changes in the environment. Electric cars are vehicles that use electricity as a source of energy instead of fossil fuel. It is possible to use the cars since they already exist in some countries (Reddy & Tharun 957). The cars are environmental friendly because they do not emit pollutants in the air. Instead of fossil fuels, they only need to be recharged using renewable sources of energy such as solar energy. The first electric car was introduced in Australia in the year 2008. Each year more of such vehicles are introduced at affordable prices (Reddy & Tharun 957). There two types of electric vehicles entail the battery-electric and hybrid-electric vehicles. The battery electric ones have rechargeable batteries that can be charged at home or at charging stations. The hybrid ones have rechargeable batteries, but they need a small amount of fossil fuel to increase its effectiveness. The distance travelled using electric vehicles varies depending on many factors just like the non-electric ones. For instance, if the road conditions are poor, one will require recharging it more times. In addition, the size of the battery will also determine the distance covered using the cars (Reddy & Tharun 957). The use of electric cars will reduce overreliance of fossil oil that has led to environmental degradation. The use of standard cars leads to the production of polluting gases such as carbon dioxide in the air. The increase in the amount of carbon dioxide and other gases produced cause the destruction of ozone layer. The layer helps in regulating the amount of heat reaching the earth. Due to the high usage of fossil fuel, this layer continues to be destroyed causing the increase in temperatures. The temperature rise has led to the degradation of the natural environment (Davis 4). For instance, temperatures

Sexism and the Star System in Architecture Essay

Sexism and the Star System in Architecture - Essay Example This kind of discrimination, unfortunately, is quite common in the profession and continues up till this day and age; it is still a major dilemma. Here, it will be attempted to describe various elements of sexism as well as those who have overcome such barriers inherent in the field of architecture, which include—but are not limited to—sexism and the star system in architecture; womens’ roles in architecture and the ideal architect profile; how kingmakers in architecture are usually men; and what it would look like if a woman were to be a kingmaker in architecture. II. Sexism and the Star System in Architecture The star system has, for a long time, dominated the way that architecture is run. The star system in architecture dominates who are the most sought-after design gurus in the field. Unfortunately, many times this system has favored men more than women in a statistical sense. Denise Scott Brown’s article Room at the Top?: Sexism and the Star System in Architecture is found in Dana Arnold’s book: â€Å"[S]exism and the star system in architecture [exists because] ‘[s]tar [q]uality’ [is] a ‘mysterious amalgam of self-love, vivacity, star, and sexual promise†¦... III. Womens’ Roles in Architecture and The Ideal Architect Profile The reason one needs to get a good architect is paramount.   A good architect on the project lays the foundation for everything else. Ideally, one wants to choose an architect for the project who has character.   In the same way this architect’s character is, so shall your structure be. Women have been at the forefront of architecture for years, but have been relegated to the shadows. â€Å"For centuries, women have designed and built works of architecture around the globe. But when architecture officially became a profession requiring professional education and licensure, the doors were slammed shut to women†¦A less-than-welcoming educational environment and a hostile [and discriminatory] work environment awaited them.†2   Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚   Women who are able to be professional in their field underscore the need for professionalism in the field of architecture. à ¢â‚¬Å"The absence of women from the profession of architecture remains, despite the various theories, very difficult to explain and slow to change. It demarcates a failure the profession has become adept at turning a blind eye to, despite the fact that it places architecture far behind the other professions with which architects frequently seek to align themselves.†3 One wants an architect who will be able to see the project through from inception to completion.   Therefore, this person is going to have to envision the project as well as bring it to fruition. Maya Lin designed the Vietnam War Veterans’ Memorial when she was a 21-year-old student. The memorial now serves as a reminder of those who fought in Vietnam and lost their lives as a result.